Can Ranitidine Cause Diaper Rash?

  • By: Julie Miller
  • Time to read: 5 min.

If your baby is experiencing a diaper rash, you may be wondering if it is caused by the Ranitidine that you are giving them. This medication is used to treat stomach ulcers and heartburn, but can it also cause diaper rash in babies?

The answer is yes, ranitidine can cause diaper rash. In this blog post, we will discuss how ranitidine causes diaper rash and how to treat this skin condition when it happens. Keep reading to know more.

Does Ranitidine Cause Diaper Rashes?

It’s possible for Ranitidine to cause irritated skin in the diaper area of a baby in the form of a diaper rash. This may be a reaction to one or more ingredients of the medication.

How to Treat Diaper Rash Caused By Ranitidine

How to Treat Diaper Rash Caused By Ranitidine

If you notice your baby has developed bright red skin in their diaper area, don’t panic! Diaper rashes are very common in babies, and there are some simple things you can do to treat them.

First, if the diaper rash is mild, you may need to use a cream that contains zinc oxide. Apply a thin layer of topical skin treatment to the diaper rash of your baby, being careful not to put on too much on the skin.

If the rash of your baby is more severe, you can try using an over-the-counter antibiotic ointment like Neosporin. This can be found at most pharmacies. Again, apply a thin layer of the cream to your baby’s skin and spread it evenly. Avoid putting on tight diapers.

If your baby is using cloth diapers, make sure to wash and rinse them properly to remove bacteria and germs. Soak them in baking soda and water before washing them to remove stains.

When cleaning your baby’s sore skin, avoid using baby wipes containing alcohol. Alcohol is an irritant that can cause further irritation. Instead, use wet a cotton ball with warm water and mild soap.

If the rash does not improve after a few days, or if it appears to be getting worse, call your doctor. They may prescribe a stronger cream or ointment to help clear up the rash.

As for diet, parents who are breastfeeding should avoid foods that are known for causing or further irritating a rash for a few weeks or until the rash is cleared.

If your baby has a yeast infection, you’ll need to change diapers more often. A diaper change should take place every two to three hours. This helps limit the exposure of your baby’s skin urine and stool. Prolonged exposure to these body wastes can irritate the rash and can lead to a yeast infection.

If the rash is severe with mild pain, you may need to change diapers more frequently. A moist environment is a breeding ground for yeast and bacteria. Be sure to clean the area well and dry it before putting on a new diaper.

In most cases, the diaper rash of a child will go away with some simple home treatment. But if parents are concerned about their baby’s rash, don’t hesitate to call the doctor. They can help you figure out the best way to treat the rashes of your newborns.


Ranitidine can cause diaper rash in some infants. If your infants experience a diaper rash while taking ranitidine, consult with your pediatrician to find an alternative medication.


What Is Ranitidine?

Ranitidine is a medication that is used to treat stomach ulcers and acid reflux. It works by reducing the amount of acid in the stomach. Ranitidine is available over-the-counter medicine.

There are many different brands and forms of ranitidine available. Some variants of ranitidine are available as a chewable tablet, an oral suspension (liquid), and an injectable form.

Ranitidine is also available as a generic drug. Generic drugs usually cost less than the brand-name version.

Ranitidine may be used as part of combination therapy. This means you may need to take it with other medicines.

Ranitidine is also available as an oral solution and effervescent tablet. These forms are not for use in children younger than 12 years old.

Be sure to check the dosage with your doctor.

What Are the Potential Side Effects of Ranitidine?

What Are the Potential Side Effects of Ranitidine?

Ranitidine may cause adverse effects. Tell your doctor if any of these symptoms are severe or do not go away after a few weeks:

  • headache
  • drowsiness
  • tiredness
  • diarrhea
  • constipation
  • upset stomach
  • vomiting

If you experience any of the following symptoms, call your doctor immediately:

  • rash
  • hives
  • itching and redness
  • difficulty breathing or swallowing
  • sore throat
  • swelling of the face, tongue, lips, and eyes
  • hoarseness
  • loose, watery stool
  • chest pain
  • fast or irregular heartbeat
  • nausea or vomiting with blood
  • black stools

What Are the Possible Drug Interactions of Ranitidine?

Ranitidine may interact with other medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements.

Be sure to make your doctors aware about all the medicines their child is taking. Drug interactions with ranitidine may occur with:

  • Antacids
  • Histamine blockers
  • Proton pump inhibitors
  • Antidepressants
  • Sedatives
  • Blood pressure medications
  • Heart rhythm medications

Why Did They Ban Ranitidine? 

Ranitidine is a H₂ blocker, which means it reduces stomach acid production. It’s available over-the-counter and by prescription, and is used to treat heartburn, ulcers, and gastroesophageal reflux disease (GERD).

On September 13, 2019, the U.S. Food and Drug Administration (FDA) issued a press release announcing that they were investigating evidence of a possible link between an increased risk of cancer and ranitidine.

As of now, the FDA has not found definitive evidence that links ranitidine and cancer. However, they are continuing to investigate the matter.

In the meantime, they have advised patients to consider using alternative treatments for their heartburn, ulcers, or GERD. Until more is known about the potential risk of cancer with ranitidine products, it is best to err on the side of caution and use an alternative treatment.

What Are Safer Alternatives to Ranitidine?

Famotidine is a histamine-blocking agent that is used to treat and prevent ulcers in patients. famotidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

Famotidine also reduces stomach acid production and is available as an over-the-counter (OTC) and prescription drug. It is also available in an injectable form to be given directly into the vein (IV) by a healthcare professional.

Famotidine should only be taken by infants if prescribed by a doctor. Just like ranitidine, it may interact with other medications.

It is still unknown if taking Famotidine during pregnancy can cause infant birth defects.

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